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Do Alterations in Mitochondrial DNA Play a Role in Breast Carcinogenesis?
A considerable body of evidence supports a role for oxidative stress in breast carcinogenesis. Due to their role in producing energy via oxidative phosphorylation, the mitochondria are a major source of production of reactive oxygen species, which may damage DNA. The mitochondrial genome may be part...
Autores principales: | Rohan, Thomas E., Wong, Lee-Jun, Wang, Tao, Haines, Jonathan, Kabat, Geoffrey C. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2902128/ https://www.ncbi.nlm.nih.gov/pubmed/20628528 http://dx.doi.org/10.1155/2010/604304 |
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