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In vitro and in vivo targeted delivery of IL-10 interfering RNA by JC virus-like particles

BACKGROUND: RNA interference (RNAi) is a powerful tool to silence gene expression post-transcriptionally. Delivering sequences of RNAi in vivo remains a problem. The aim of this study was to use JC virus (JCV) virus-like particles (VLPs) as a vector for delivering RNAi in silencing the cytokine gene...

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Detalles Bibliográficos
Autores principales: Chou, Meng-Ing, Hsieh, Yu-Fan, Wang, Meilin, Chang, Jinghua Tsai, Chang, Deching, Zouali, Moncef, Tsay, Gregory J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2902427/
https://www.ncbi.nlm.nih.gov/pubmed/20573280
http://dx.doi.org/10.1186/1423-0127-17-51