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In vitro and in vivo targeted delivery of IL-10 interfering RNA by JC virus-like particles
BACKGROUND: RNA interference (RNAi) is a powerful tool to silence gene expression post-transcriptionally. Delivering sequences of RNAi in vivo remains a problem. The aim of this study was to use JC virus (JCV) virus-like particles (VLPs) as a vector for delivering RNAi in silencing the cytokine gene...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2902427/ https://www.ncbi.nlm.nih.gov/pubmed/20573280 http://dx.doi.org/10.1186/1423-0127-17-51 |