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Signal transduction mechanisms involved in S100A4-induced activation of the transcription factor NF-κB

BACKGROUND: The metastasis-promoting protein S100A4 activates the transcription factor NF-κB through the classical NF-κB activation pathway. The upstream signal transduction mechanisms leading to increased NF-κB activity are, however, incompletely characterized. METHODS: The human osteosarcoma cell...

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Detalles Bibliográficos
Autores principales: Grotterød, Ida, Mælandsmo, Gunhild M, Boye, Kjetil
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2902441/
https://www.ncbi.nlm.nih.gov/pubmed/20507646
http://dx.doi.org/10.1186/1471-2407-10-241