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Myc suppression of Nfkb2 accelerates lymphomagenesis

BACKGROUND: Deregulated c-Myc expression is a hallmark of several human cancers where it promotes proliferation and an aggressive tumour phenotype. Myc overexpression is associated with reduced activity of Rel/NF-κB, transcription factors that control the immune response, cell survival, and transfor...

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Detalles Bibliográficos
Autores principales: Keller, Ulrich, Huber, Jürgen, Nilsson, Jonas A, Fallahi, Mohammad, Hall, Mark A, Peschel, Christian, Cleveland, John L
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2902445/
https://www.ncbi.nlm.nih.gov/pubmed/20598117
http://dx.doi.org/10.1186/1471-2407-10-348