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Neuroinflammation in Lyme neuroborreliosis affects amyloid metabolism
BACKGROUND: The metabolism of amyloid precursor protein (APP) and β-amyloid (Aβ) is widely studied in Alzheimer's disease, where Aβ deposition and plaque development are essential components of the pathogenesis. However, the physiological role of amyloid in the adult nervous system remains larg...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2902447/ https://www.ncbi.nlm.nih.gov/pubmed/20569437 http://dx.doi.org/10.1186/1471-2377-10-51 |