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New clinically relevant, orthotopic mouse models of human chondrosarcoma with spontaneous metastasis

BACKGROUND: Chondrosarcoma responds poorly to adjuvant therapy and new, clinically relevant animal models are required to test targeted therapy. METHODS: Two human chondrosarcoma cell lines, JJ012 and FS090, were evaluated for proliferation, colony formation, invasion, angiogenesis and osteoclastoge...

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Detalles Bibliográficos
Autores principales: Clark, Jonathan CM, Akiyama, Toru, Dass, Crispin R, Choong, Peter FM
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2902463/
https://www.ncbi.nlm.nih.gov/pubmed/20584302
http://dx.doi.org/10.1186/1475-2867-10-20