Transcriptional upregulation of both egl-1 BH3-only and ced-3 caspase is required for the death of the male-specific CEM neurons

Most of the 131 cells that die during the development of a C. elegans hermaphrodite do so ~30 min after being generated. Furthermore, in these cells, the pro-caspase proCED-3 is inherited from progenitors and the transcriptional upregulation of the BH3-only gene egl-1 is thought to be sufficient for...

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Detalles Bibliográficos
Autores principales: Nehme, Ralda, Grote, Phillip, Tomasi, Tatiana, Löser, Stefanie, Holzkamp, Heinke, Schnabel, Ralf, Conradt, Barbara
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2902690/
https://www.ncbi.nlm.nih.gov/pubmed/20150917
http://dx.doi.org/10.1038/cdd.2010.3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2902690/
https://www.ncbi.nlm.nih.gov/pubmed/20150917
http://dx.doi.org/10.1038/cdd.2010.3

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