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VEGF Induces More Severe Cerebrovascular Dysplasia in Eng(+/−) than in Alk1(+/−) Mice
Brain arteriovenous malformations (BAVMs) are an important cause of intracranial hemorrhage (ICH) in young adults. A small percent of BAVMs is due to hereditary hemorrhagic telangiectasia 1 and 2 (HHT1 and 2), which are caused by mutations in two genes involved in transforming growth factor-β signal...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2902730/ https://www.ncbi.nlm.nih.gov/pubmed/20640035 http://dx.doi.org/10.1007/s12975-010-0020-x |