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Hsp90 as a Gatekeeper of Tumor Angiogenesis: Clinical Promise and Potential Pitfalls

Tumor vascularization is an essential modulator of early tumor growth, progression, and therapeutic outcome. Although antiangiogenic treatments appear promising, intrinsic and acquired tumor resistance contributes to treatment failure. Clinical inhibition of the molecular chaperone heat shock protei...

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Detalles Bibliográficos
Autores principales: Bohonowych, J. E., Gopal, U., Isaacs, J. S.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2902748/
https://www.ncbi.nlm.nih.gov/pubmed/20628489
http://dx.doi.org/10.1155/2010/412985