The First Human Epitope Map of the Alphaviral E1 and E2 Proteins Reveals a New E2 Epitope with Significant Virus Neutralizing Activity

BACKGROUND: Venezuelan equine encephalitis virus (VEEV) is responsible for VEE epidemics that occur in South and Central America and the U.S. The VEEV envelope contains two glycoproteins E1 (mediates cell membrane fusion) and E2 (binds receptor and elicits virus neutralizing antibodies). Previously...

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Detalles Bibliográficos
Autores principales: Hunt, Ann R., Frederickson, Shana, Maruyama, Toshiaki, Roehrig, John T., Blair, Carol D.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2903468/
https://www.ncbi.nlm.nih.gov/pubmed/20644615
http://dx.doi.org/10.1371/journal.pntd.0000739

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2903468/
https://www.ncbi.nlm.nih.gov/pubmed/20644615
http://dx.doi.org/10.1371/journal.pntd.0000739

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