In Vitro and In Vivo High-Throughput Assays for the Testing of Anti-Trypanosoma cruzi Compounds

BACKGROUND: The two available drugs for treatment of T. cruzi infection, nifurtimox and benznidazole (BZ), have potential toxic side effects and variable efficacy, contributing to their low rate of use. With scant economic resources available for antiparasitic drug discovery and development, inexpen...

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Detalles Bibliográficos
Autores principales: Canavaci, Adriana M. C., Bustamante, Juan M., Padilla, Angel M., Perez Brandan, Cecilia M., Simpson, Laura J., Xu, Dan, Boehlke, Courtney L., Tarleton, Rick L.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2903469/
https://www.ncbi.nlm.nih.gov/pubmed/20644616
http://dx.doi.org/10.1371/journal.pntd.0000740

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2903469/
https://www.ncbi.nlm.nih.gov/pubmed/20644616
http://dx.doi.org/10.1371/journal.pntd.0000740

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