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DNA Replication Is Intrinsically Hindered in Terminally Differentiated Myotubes

BACKGROUND: Terminally differentiated (TD) cells permanently exit the mitotic cycle while acquiring specialized characteristics. Although TD cells can be forced to reenter the cell cycle by different means, they cannot be made to stably proliferate, as attempts to induce their replication constantly...

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Detalles Bibliográficos
Autores principales: Pajalunga, Deborah, Puggioni, Eleonora M. R., Mazzola, Alessia, Leva, Valentina, Montecucco, Alessandra, Crescenzi, Marco
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2903488/
https://www.ncbi.nlm.nih.gov/pubmed/20644635
http://dx.doi.org/10.1371/journal.pone.0011559