Study of Transcriptional Effects in Cis at the IFIH1 Locus

BACKGROUND: The Thr allele at the non-synonymous single-nucleotide polymorphism (nsSNP) Thr946Ala in the IFIH1 gene confers risk for Type 1 diabetes (T1D). The SNP is embedded in a 236 kb linkage disequilibrium (LD) block that includes four genes: IFIH1, GCA, FAP and KCNH7. The absence of common nsS...

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Detalles Bibliográficos
Autores principales: Zouk, Hana, Marchand, Luc, Polychronakos, Constantin
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2903489/
https://www.ncbi.nlm.nih.gov/pubmed/20644636
http://dx.doi.org/10.1371/journal.pone.0011564

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2903489/
https://www.ncbi.nlm.nih.gov/pubmed/20644636
http://dx.doi.org/10.1371/journal.pone.0011564

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