Epigenetic repression of ROR2 has a Wnt-mediated, pro-tumourigenic role in colon cancer

BACKGROUND: Wnt factors control cell differentiation through semi-independent molecular cascades known as the β-catenin-dependent (canonical) and -independent (non-canonical) Wnt signalling pathways. Genetic and epigenetic alteration of components of the canonical Wnt signalling pathway is one of th...

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Detalles Bibliográficos
Autores principales: Lara, Ester, Calvanese, Vincenzo, Huidobro, Covadonga, Fernández, Agustin F, Moncada-Pazos, Ángela, Obaya, Álvaro J, Aguilera, Oscar, González-Sancho, José Manuel, Sánchez, Laura, Astudillo, Aurora, Muñoz, Alberto, López-Otín, Carlos, Esteller, Manel, Fraga, Mario F
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2903502/
https://www.ncbi.nlm.nih.gov/pubmed/20591152
http://dx.doi.org/10.1186/1476-4598-9-170

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2903502/
https://www.ncbi.nlm.nih.gov/pubmed/20591152
http://dx.doi.org/10.1186/1476-4598-9-170

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