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Epigenetic repression of ROR2 has a Wnt-mediated, pro-tumourigenic role in colon cancer

BACKGROUND: Wnt factors control cell differentiation through semi-independent molecular cascades known as the β-catenin-dependent (canonical) and -independent (non-canonical) Wnt signalling pathways. Genetic and epigenetic alteration of components of the canonical Wnt signalling pathway is one of th...

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Detalles Bibliográficos
Autores principales:	Lara, Ester, Calvanese, Vincenzo, Huidobro, Covadonga, Fernández, Agustin F, Moncada-Pazos, Ángela, Obaya, Álvaro J, Aguilera, Oscar, González-Sancho, José Manuel, Sánchez, Laura, Astudillo, Aurora, Muñoz, Alberto, López-Otín, Carlos, Esteller, Manel, Fraga, Mario F
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2903502/ https://www.ncbi.nlm.nih.gov/pubmed/20591152 http://dx.doi.org/10.1186/1476-4598-9-170

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