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Hyperinsulinemia improves ischemic LV function in insulin resistant subjects

BACKGROUND: Glucose is a more efficient substrate for ATP production than free fatty acid (FFA). Insulin resistance (IR) results in higher FFA concentrations and impaired myocardial glucose use, potentially worsening ischemia. We hypothesized that metabolic manipulation with a hyperinsulinemic eugly...

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Detalles Bibliográficos
Autores principales: Heck, Patrick M, Hoole, Stephen P, Khan, Sadia N, Dutka, David P
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2903514/
https://www.ncbi.nlm.nih.gov/pubmed/20576156
http://dx.doi.org/10.1186/1475-2840-9-27