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Hsa-miR-125a-3p and hsa-miR-125a-5p are downregulated in non-small cell lung cancer and have inverse effects on invasion and migration of lung cancer cells

BACKGROUND: Two mature microRNAs (miRNAs), hsa-miR-125a-3p and hsa-miR-125a-5p (collectively referred to as hsa-miR-125a-3p/5p), are derived from 3' and 5' ends of pre-miR-125a, respectively. Although impaired regulation of hsa-miR-125a-5p has been observed in some tumors, the role of this...

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Detalles Bibliográficos
Autores principales: Jiang, Lili, Huang, Qin, Zhang, Siyang, Zhang, Qingfu, Chang, Jihong, Qiu, Xueshan, Wang, Enhua
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2903529/
https://www.ncbi.nlm.nih.gov/pubmed/20569443
http://dx.doi.org/10.1186/1471-2407-10-318