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Revealing and avoiding bias in semantic similarity scores for protein pairs

BACKGROUND: Semantic similarity scores for protein pairs are widely applied in functional genomic researches for finding functional clusters of proteins, predicting protein functions and protein-protein interactions, and for identifying putative disease genes. However, because some proteins, such as...

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Detalles Bibliográficos
Autores principales: Wang, Jing, Zhou, Xianxiao, Zhu, Jing, Zhou, Chenggui, Guo, Zheng
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2903568/
https://www.ncbi.nlm.nih.gov/pubmed/20509916
http://dx.doi.org/10.1186/1471-2105-11-290