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Prediction of epigenetically regulated genes in breast cancer cell lines

BACKGROUND: Methylation of CpG islands within the DNA promoter regions is one mechanism that leads to aberrant gene expression in cancer. In particular, the abnormal methylation of CpG islands may silence associated genes. Therefore, using high-throughput microarrays to measure CpG island methylatio...

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Detalles Bibliográficos
Autores principales: Loss, Leandro A, Sadanandam, Anguraj, Durinck, Steffen, Nautiyal, Shivani, Flaucher, Diane, Carlton, Victoria EH, Moorhead, Martin, Lu, Yontao, Gray, Joe W, Faham, Malek, Spellman, Paul, Parvin, Bahram
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2903569/
https://www.ncbi.nlm.nih.gov/pubmed/20525369
http://dx.doi.org/10.1186/1471-2105-11-305