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Activated networking of platelet activating factor receptor and FAK/STAT1 induces malignant potential in BRCA1-mutant at-risk ovarian epithelium

OBJECTIVES: It is essential to understand the molecular basis of ovarian cancer etiology and tumor development to provide more effective preventive and therapeutic approaches to reduce mortality. Particularly, the molecular targets and pathways involved in early malignant transformation are still no...

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Detalles Bibliográficos
Autores principales: Zhang, Lifang, Wang, Dan, Jiang, Wei, Edwards, Dale, Qiu, Weiliang, Barroilhet, Lisa M, Rho, Jung-hyun, Jin, Lianjin, Seethappan, Vanitha, Vitonis, Allison, Wang, Jianliu, Mok, Samuel C, Crum, Christopher, Cramer, Daniel W, Ye, Bin
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2903602/
https://www.ncbi.nlm.nih.gov/pubmed/20576130
http://dx.doi.org/10.1186/1477-7827-8-74