Aurora-C Kinase Deficiency Causes Cytokinesis Failure in Meiosis I and Production of Large Polyploid Oocytes in Mice

We previously isolated Aurora-C/Aie1 in a screen for kinases expressed in mouse sperm and eggs. Here, we show the localization of endogenous Aurora-C and examine its roles during female mouse meiosis. Aurora-C was detected at the centromeres and along the chromosome arms in prometaphase I–metaphase...

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Detalles Bibliográficos
Autores principales: Yang, Kuo-Tai, Li, Shu-Kuei, Chang, Chih-Chieh, Tang, Chieh-Ju C., Lin, Yi-Nan, Lee, Sheng-Chung, Tang, Tang K.
Formato: Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2010
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2903667/
https://www.ncbi.nlm.nih.gov/pubmed/20484572
http://dx.doi.org/10.1091/mbc.E10-02-0170

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2903667/
https://www.ncbi.nlm.nih.gov/pubmed/20484572
http://dx.doi.org/10.1091/mbc.E10-02-0170

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