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Unrestrained Spindle Elongation during Recovery from Spindle Checkpoint Activation in cdc15-2 Cells Results in Mis-Segregation of Chromosomes

During normal metaphase in Saccharomyces cerevisiae, chromosomes are captured at the kinetochores by microtubules emanating from the spindle pole bodies at opposite poles of the dividing cell. The balance of forces between the cohesins holding the replicated chromosomes together and the pulling forc...

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Detalles Bibliográficos
Autores principales: Chai, Chuan Chung, Teh, Ee Mei, Yeong, Foong May
Formato: Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2903668/
https://www.ncbi.nlm.nih.gov/pubmed/20505077
http://dx.doi.org/10.1091/mbc.E09-07-0637