Cargando…

Scyl1 Facilitates Nuclear tRNA Export in Mammalian Cells by Acting at the Nuclear Pore Complex

Scyl1 is an evolutionarily conserved N-terminal protein kinase-like domain protein that plays a role in COP1-mediated retrograde protein trafficking in mammalian cells. Furthermore, loss of Scyl1 function has been shown to result in neurodegenerative disorders in mice. Here, we report that Scyl1 is...

Descripción completa

Detalles Bibliográficos
Autores principales: Chafe, Shawn C., Mangroo, Dev
Formato: Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2903676/
https://www.ncbi.nlm.nih.gov/pubmed/20505071
http://dx.doi.org/10.1091/mbc.E10-03-0176