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Atrial arrhythmogenicity in aged Scn5a+/∆KPQ mice modeling long QT type 3 syndrome and its relationship to Na(+) channel expression and cardiac conduction

Recent studies have reported that human mutations in Nav1.5 predispose to early age onset atrial arrhythmia. The present experiments accordingly assess atrial arrhythmogenicity in aging Scn5a+/∆KPQ mice modeling long QT3 syndrome in relationship to cardiac Na(+) channel, Nav1.5, expression. Atrial e...

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Detalles Bibliográficos
Autores principales: Guzadhur, Laila, Pearcey, Sarah M., Duehmke, Rudolf M., Jeevaratnam, Kamalan, Hohmann, Anja F., Zhang, Yanmin, Grace, Andrew A., Lei, Ming, Huang, Christopher L.-H.
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2903684/
https://www.ncbi.nlm.nih.gov/pubmed/20552221
http://dx.doi.org/10.1007/s00424-010-0851-z