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Atrial arrhythmogenicity in aged Scn5a+/∆KPQ mice modeling long QT type 3 syndrome and its relationship to Na(+) channel expression and cardiac conduction
Recent studies have reported that human mutations in Nav1.5 predispose to early age onset atrial arrhythmia. The present experiments accordingly assess atrial arrhythmogenicity in aging Scn5a+/∆KPQ mice modeling long QT3 syndrome in relationship to cardiac Na(+) channel, Nav1.5, expression. Atrial e...
Autores principales: | Guzadhur, Laila, Pearcey, Sarah M., Duehmke, Rudolf M., Jeevaratnam, Kamalan, Hohmann, Anja F., Zhang, Yanmin, Grace, Andrew A., Lei, Ming, Huang, Christopher L.-H. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2903684/ https://www.ncbi.nlm.nih.gov/pubmed/20552221 http://dx.doi.org/10.1007/s00424-010-0851-z |
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