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Bile acids regulate hepatic gluconeogenic genes and farnesoid X receptor via Gα(i)-protein-coupled receptors and the AKT pathway

Bile acids are important regulatory molecules that can activate specific nuclear receptors and cell signaling pathways in the liver and gastrointestinal tract. In the current study, the chronic bile fistula (CBF) rat model and primary rat hepatocytes (PRH) were used to study the regulation of glucon...

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Detalles Bibliográficos
Autores principales: Cao, Risheng, Cronk, Zhumei Xu, Zha, Weibin, Sun, Lixin, Wang, Xuan, Fang, Youwen, Studer, Elaine, Zhou, Huiping, Pandak, William M., Dent, Paul, Gil, Gregorio, Hylemon, Phillip B.
Formato: Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2903791/
https://www.ncbi.nlm.nih.gov/pubmed/20305288
http://dx.doi.org/10.1194/jlr.M004929