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First evidence of overlaps between HIV-Associated Dementia (HAD) and non-viral neurodegenerative diseases: proteomic analysis of the frontal cortex from HIV+ patients with and without dementia

BACKGROUND: The pathogenesis of HIV-associated dementia (HAD) is poorly understood. To date, detailed proteomic fingerprinting directly from autopsied brain tissues of HAD and HIV non-dementia patients has not been performed. RESULT: Here, we have analyzed total proteins from the frontal cortex of 9...

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Detalles Bibliográficos
Autores principales: Zhou, Li, Diefenbach, Eve, Crossett, Ben, Tran, Sieu L, Ng, Thomas, Rizos, Helen, Rua, Rejane, Wang, Bin, Kapur, Amit, Gandhi, Kaushal, Brew, Bruce J, Saksena, Nitin K
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2904315/
https://www.ncbi.nlm.nih.gov/pubmed/20573273
http://dx.doi.org/10.1186/1750-1326-5-27