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Comparison of Plasmodium berghei challenge models for the evaluation of pre-erythrocytic malaria vaccines and their effect on perceived vaccine efficacy

BACKGROUND: The immunological mechanisms responsible for protection against malaria infection vary among Plasmodium species, host species and the developmental stage of parasite, and are poorly understood. A challenge with live parasites is the most relevant approach to testing the efficacy of exper...

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Detalles Bibliográficos
Autores principales: Leitner, Wolfgang W, Bergmann-Leitner, Elke S, Angov, Evelina
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2904356/
https://www.ncbi.nlm.nih.gov/pubmed/20507620
http://dx.doi.org/10.1186/1475-2875-9-145