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Comparison of Plasmodium berghei challenge models for the evaluation of pre-erythrocytic malaria vaccines and their effect on perceived vaccine efficacy
BACKGROUND: The immunological mechanisms responsible for protection against malaria infection vary among Plasmodium species, host species and the developmental stage of parasite, and are poorly understood. A challenge with live parasites is the most relevant approach to testing the efficacy of exper...
Autores principales: | Leitner, Wolfgang W, Bergmann-Leitner, Elke S, Angov, Evelina |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2904356/ https://www.ncbi.nlm.nih.gov/pubmed/20507620 http://dx.doi.org/10.1186/1475-2875-9-145 |
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