Cargando…

LRP-1 Promotes Cancer Cell Invasion by Supporting ERK and Inhibiting JNK Signaling Pathways

BACKGROUND: The low-density lipoprotein receptor-related protein-1 (LRP-1) is an endocytic receptor mediating the clearance of various extracellular molecules involved in the dissemination of cancer cells. LRP-1 thus appeared as an attractive receptor for targeting the invasive behavior of malignant...

Descripción completa

Detalles Bibliográficos
Autores principales: Langlois, Benoit, Perrot, Gwenn, Schneider, Christophe, Henriet, Patrick, Emonard, Hervé, Martiny, Laurent, Dedieu, Stéphane
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2904376/
https://www.ncbi.nlm.nih.gov/pubmed/20644732
http://dx.doi.org/10.1371/journal.pone.0011584