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LRP-1 Promotes Cancer Cell Invasion by Supporting ERK and Inhibiting JNK Signaling Pathways
BACKGROUND: The low-density lipoprotein receptor-related protein-1 (LRP-1) is an endocytic receptor mediating the clearance of various extracellular molecules involved in the dissemination of cancer cells. LRP-1 thus appeared as an attractive receptor for targeting the invasive behavior of malignant...
Autores principales: | Langlois, Benoit, Perrot, Gwenn, Schneider, Christophe, Henriet, Patrick, Emonard, Hervé, Martiny, Laurent, Dedieu, Stéphane |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2904376/ https://www.ncbi.nlm.nih.gov/pubmed/20644732 http://dx.doi.org/10.1371/journal.pone.0011584 |
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