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Expression of Wild-Type CFTR Suppresses NF-κB-Driven Inflammatory Signalling

BACKGROUND: Mutation of the cystic fibrosis transmembrane-conductance regulator (CFTR) causes cystic fibrosis (CF) but not all CF aspects can easily be explained by deficient ion transport. CF-inflammation provides one example but its pathogenesis remains controversial. Here, we tested the simple bu...

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Detalles Bibliográficos
Autores principales: Hunter, Mairi J., Treharne, Kate J., Winter, Alexandra K., Cassidy, Diane M., Land, Stephen, Mehta, Anil
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2904384/
https://www.ncbi.nlm.nih.gov/pubmed/20644644
http://dx.doi.org/10.1371/journal.pone.0011598