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Activation of Hypoxia Inducible Factor 1 Is a General Phenomenon in Infections with Human Pathogens

BACKGROUND: Hypoxia inducible factor (HIF)-1 is the key transcriptional factor involved in the adaptation process of cells and organisms to hypoxia. Recent findings suggest that HIF-1 plays also a crucial role in inflammatory and infectious diseases. METHODOLOGY/PRINCIPAL FINDINGS: Using patient ski...

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Detalles Bibliográficos
Autores principales: Werth, Nadine, Beerlage, Christiane, Rosenberger, Christian, Yazdi, Amir S., Edelmann, Markus, Amr, Amro, Bernhardt, Wanja, von Eiff, Christof, Becker, Karsten, Schäfer, Andrea, Peschel, Andreas, Kempf, Volkhard A. J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2904385/
https://www.ncbi.nlm.nih.gov/pubmed/20644645
http://dx.doi.org/10.1371/journal.pone.0011576