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Tumor Necrosis Factor Receptor Associated Factor 6 Is Not Required for Atherogenesis in Mice and Does Not Associate with Atherosclerosis in Humans

BACKGROUND: Tumor necrosis factor receptor-associated factors (TRAFs) are important signaling molecules for a variety of pro-atherogenic cytokines including CD40L, TNF α, and IL1β. Several lines of evidence identified TRAF6 as a pro-inflammatory signaling molecule in vitro and we previously demonstr...

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Detalles Bibliográficos
Autores principales: Stachon, Peter, Missiou, Anna, Walter, Carina, Varo, Nerea, Colberg, Christian, Wolf, Dennis, Buchner, Maike, von zur Mühlen, Constantin, Zirlik, Katja, Bode, Christoph, Zirlik, Andreas
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2904388/
https://www.ncbi.nlm.nih.gov/pubmed/20644648
http://dx.doi.org/10.1371/journal.pone.0011589