The TLR4/TRIF-Mediated Activation of NLRP3 Inflammasome Underlies Endotoxin-Induced Liver Injury in Mice

Administration of heat-killed Propionibacterium acnes renders mice highly susceptible to LPS. After LPS challenge P. acnes-primed mice promptly show hypothermia, hypercoagulation (disseminated intravascular coagulation), elevation of serum proinflammatory cytokine levels, and high mortality. The sur...

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Detalles Bibliográficos
Autores principales: Tsutsui, Hiroko, Imamura, Michiko, Fujimoto, Jiro, Nakanishi, Kenji
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2010
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2904443/
https://www.ncbi.nlm.nih.gov/pubmed/20634907
http://dx.doi.org/10.1155/2010/641865

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2904443/
https://www.ncbi.nlm.nih.gov/pubmed/20634907
http://dx.doi.org/10.1155/2010/641865

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