Activation of PmrA inhibits LpxT-dependent phosphorylation of lipid A promoting resistance to antimicrobial peptides

During its transport to the bacterial surface, the phosphate groups of the lipid A anchor of Escherichia coli and Salmonella lipopolysaccharide are modified by membrane enzymes including ArnT, EptA and LpxT. ArnT and EptA catalyse the periplasmic addition of the positively charged substituents 4-ami...

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Detalles Bibliográficos
Autores principales: Herrera, Carmen M, Hankins, Jessica V, Trent, M Stephen
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2010
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2904496/
https://www.ncbi.nlm.nih.gov/pubmed/20384697
http://dx.doi.org/10.1111/j.1365-2958.2010.07150.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2904496/
https://www.ncbi.nlm.nih.gov/pubmed/20384697
http://dx.doi.org/10.1111/j.1365-2958.2010.07150.x

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