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Activation of PmrA inhibits LpxT-dependent phosphorylation of lipid A promoting resistance to antimicrobial peptides

During its transport to the bacterial surface, the phosphate groups of the lipid A anchor of Escherichia coli and Salmonella lipopolysaccharide are modified by membrane enzymes including ArnT, EptA and LpxT. ArnT and EptA catalyse the periplasmic addition of the positively charged substituents 4-ami...

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Detalles Bibliográficos
Autores principales:	Herrera, Carmen M, Hankins, Jessica V, Trent, M Stephen
Formato:	Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2010
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2904496/ https://www.ncbi.nlm.nih.gov/pubmed/20384697 http://dx.doi.org/10.1111/j.1365-2958.2010.07150.x

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