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In acute pathogenic SIV infection plasmacytoid dendritic cells are depleted from blood and lymph nodes despite mobilization

Background  Plasmacytoid dendritic cells (pDC) are depleted from blood of individuals with HIV infection associated with progression to disease. It has been postulated but not proven that pDC accumulate in lymph nodes and induce sustained immune activation characteristic of disease. Methods  The dyn...

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Detalles Bibliográficos
Autores principales: Barratt‐Boyes, Simon M., Wijewardana, Viskam, Brown, Kevin N.
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2904653/
https://www.ncbi.nlm.nih.gov/pubmed/20618589
http://dx.doi.org/10.1111/j.1600-0684.2010.00428.x