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Constitutive glycogen synthase kinase-3α/β activity protects against chronic β-adrenergic remodelling of the heart
AIMS: Glycogen synthase kinase 3 (GSK-3) signalling is implicated in the growth of the heart during development and in response to stress. However, its precise role remains unclear. We set out to characterize developmental growth and response to chronic isoproterenol (ISO) stress in knockin (KI) mic...
Autores principales: | , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2904659/ https://www.ncbi.nlm.nih.gov/pubmed/20299330 http://dx.doi.org/10.1093/cvr/cvq061 |