Constitutive glycogen synthase kinase-3α/β activity protects against chronic β-adrenergic remodelling of the heart

AIMS: Glycogen synthase kinase 3 (GSK-3) signalling is implicated in the growth of the heart during development and in response to stress. However, its precise role remains unclear. We set out to characterize developmental growth and response to chronic isoproterenol (ISO) stress in knockin (KI) mic...

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Detalles Bibliográficos
Autores principales: Webb, Ian G., Nishino, Yasuhiro, Clark, James E., Murdoch, Colin, Walker, Simon J., Makowski, Marcus R., Botnar, Rene M., Redwood, Simon R., Shah, Ajay M., Marber, Michael S.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2904659/
https://www.ncbi.nlm.nih.gov/pubmed/20299330
http://dx.doi.org/10.1093/cvr/cvq061

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