Essential Role of Neuron-Enriched Diacylglycerol Kinase (DGK), DGKβ in Neurite Spine Formation, Contributing to Cognitive Function

BACKGROUND: Diacylglycerol (DG) kinase (DGK) phosphorylates DG to produce phosphatidic acid (PA). Of the 10 subtypes of mammalian DGKs, DGKβ is a membrane-localized subtype and abundantly expressed in the cerebral cortex, hippocampus, and caudate-putamen. However, its physiological roles in neurons...

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Detalles Bibliográficos
Autores principales: Shirai, Yasuhito, Kouzuki, Takeshi, Kakefuda, Kenichi, Moriguchi, Shigeki, Oyagi, Atsushi, Horie, Kyoji, Morita, Shin-ya, Shimazawa, Masamitsu, Fukunaga, Kohji, Takeda, Junji, Saito, Naoaki, Hara, Hideaki
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2904696/
https://www.ncbi.nlm.nih.gov/pubmed/20657643
http://dx.doi.org/10.1371/journal.pone.0011602

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2904696/
https://www.ncbi.nlm.nih.gov/pubmed/20657643
http://dx.doi.org/10.1371/journal.pone.0011602

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