MMP-9, uPAR and Cathepsin B Silencing Downregulate Integrins in Human Glioma Xenograft Cells In Vitro and In Vivo in Nude Mice

BACKGROUND: Involvement of MMP-9, uPAR and cathepsin B in adhesion, migration, invasion, proliferation, metastasis and tumor growth has been well established. In the present study, MMP-9, uPAR and cathepsin B genes were downregulated in glioma xenograft cells using shRNA plasmid constructs and we ev...

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Detalles Bibliográficos
Autores principales: Veeravalli, Krishna Kumar, Chetty, Chandramu, Ponnala, Shivani, Gondi, Christopher S., Lakka, Sajani S., Fassett, Daniel, Klopfenstein, Jeffrey D., Dinh, Dzung H., Gujrati, Meena, Rao, Jasti S.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2904700/
https://www.ncbi.nlm.nih.gov/pubmed/20657647
http://dx.doi.org/10.1371/journal.pone.0011583

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2904700/
https://www.ncbi.nlm.nih.gov/pubmed/20657647
http://dx.doi.org/10.1371/journal.pone.0011583

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