Two Origins for the Gene Encoding α-Isopropylmalate Synthase in Fungi

BACKGROUND: The biosynthesis of leucine is a biochemical pathway common to prokaryotes, plants and fungi, but absent from humans and animals. The pathway is a proposed target for antimicrobial therapy. METHODOLOGY/PRINCIPAL FINDINGS: Here we identified the leuA gene encoding α-isopropylmalate syntha...

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Detalles Bibliográficos
Autores principales: Larson, Erica M., Idnurm, Alexander
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2904702/
https://www.ncbi.nlm.nih.gov/pubmed/20657649
http://dx.doi.org/10.1371/journal.pone.0011605

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2904702/
https://www.ncbi.nlm.nih.gov/pubmed/20657649
http://dx.doi.org/10.1371/journal.pone.0011605

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