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Two Origins for the Gene Encoding α-Isopropylmalate Synthase in Fungi
BACKGROUND: The biosynthesis of leucine is a biochemical pathway common to prokaryotes, plants and fungi, but absent from humans and animals. The pathway is a proposed target for antimicrobial therapy. METHODOLOGY/PRINCIPAL FINDINGS: Here we identified the leuA gene encoding α-isopropylmalate syntha...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2904702/ https://www.ncbi.nlm.nih.gov/pubmed/20657649 http://dx.doi.org/10.1371/journal.pone.0011605 |