DCB-3503, a Tylophorine Analog, Inhibits Protein Synthesis through a Novel Mechanism

BACKGROUND: DCB-3503, a tylophorine analog, inhibits the growth of PANC-1 (human pancreatic ductal cancer cell line) and HepG2 (human hepatocellular cancer cell line) tumor xenografts in nude mice. The inhibition of growth leads to cancer cell differentiation instead of cell death. However, the mech...

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Detalles Bibliográficos
Autores principales: Wang, Ying, Gao, Wenli, Svitkin, Yuri V., Chen, Annie Pei-Chun, Cheng, Yung-Chi
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2904705/
https://www.ncbi.nlm.nih.gov/pubmed/20657652
http://dx.doi.org/10.1371/journal.pone.0011607

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2904705/
https://www.ncbi.nlm.nih.gov/pubmed/20657652
http://dx.doi.org/10.1371/journal.pone.0011607

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