Cargando…

Genome-Wide Scoring of Positive and Negative Epistasis through Decomposition of Quantitative Genetic Interaction Fitness Matrices

Recent technological developments in genetic screening approaches have offered the means to start exploring quantitative genotype-phenotype relationships on a large-scale. What remains unclear is the extent to which the quantitative genetic interaction datasets can distinguish the broad spectrum of...

Descripción completa

Detalles Bibliográficos
Autores principales: Eronen, Ville-Pekka, Lindén, Rolf O., Lindroos, Anna, Kanerva, Mirella, Aittokallio, Tero
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2904709/
https://www.ncbi.nlm.nih.gov/pubmed/20657656
http://dx.doi.org/10.1371/journal.pone.0011611