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Zinc Finger Nucleases as tools to understand and treat human diseases

Recent work has shown that it is possible to target regulatory elements to DNA sequences of an investigator's choosing, increasing the armamentarium for probing gene function. In this review, we discuss the development and use of designer zinc finger proteins (ZFPs) as sequence specific tools....

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Detalles Bibliográficos
Autores principales: Davis, David, Stokoe, David
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2904710/
https://www.ncbi.nlm.nih.gov/pubmed/20594338
http://dx.doi.org/10.1186/1741-7015-8-42