Cargando…
Zinc Finger Nucleases as tools to understand and treat human diseases
Recent work has shown that it is possible to target regulatory elements to DNA sequences of an investigator's choosing, increasing the armamentarium for probing gene function. In this review, we discuss the development and use of designer zinc finger proteins (ZFPs) as sequence specific tools....
Autores principales: | Davis, David, Stokoe, David |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2904710/ https://www.ncbi.nlm.nih.gov/pubmed/20594338 http://dx.doi.org/10.1186/1741-7015-8-42 |
Ejemplares similares
-
Evaluation of Novel Design Strategies for Developing Zinc Finger Nucleases Tools for Treating Human Diseases
por: Bach, Christian, et al.
Publicado: (2014) -
Targeted genome engineering via zinc finger nucleases
por: Kim, Seokjoong, et al.
Publicado: (2010) -
Zinc Finger Nucleases: A new era for transgenic animals
por: Swarthout, John T., et al.
Publicado: (2011) -
Genome editing in plants via designed zinc finger nucleases
por: Petolino, Joseph F.
Publicado: (2015) -
Zinc Finger Tools: custom DNA-binding domains for transcription factors and nucleases
por: Mandell, Jeffrey G., et al.
Publicado: (2006)