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An insertion mutation in ABCB4 is associated with gallbladder mucocele formation in dogs
BACKGROUND: ABCB4 functions as a phosphatidylcholine translocater, flipping phosphatidylcholine across hepatocyte canalicular membranes into biliary canaliculi. In people, ABCB4 gene mutations are associated with several disease syndromes including intrahepatic cholestasis of pregnancy, progressive...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2904718/ https://www.ncbi.nlm.nih.gov/pubmed/20598156 http://dx.doi.org/10.1186/1476-5926-9-6 |